Multiplayer only, since I don't really play solo:
Rounds 1-4 camp in the centrifuge room doing the pistol for max points trick.
Round 5-7 camp in the room with the Stakeout and the first random box.
Round 8-12 work on getting the landers and the PaP and a bunch of points.
Round 13 spam the random box for a Ray Gun, Gersh devices and, if possible, Thundergun.
Round 14 buy jugger-nog and fend off the monkeys to gain new perk.
Rounds 17+ camp in the PhD flopper lander location.
It works pretty well for me until people start freaking out about no ammo and try to get power-ups from the bottom of the stairs. One person goes down, and the rest fall like dominoes.